Katz D A, Naseem A, Horoupian D S, Rothner A D, Davies P
Neurology. 1984 Sep;34(9):1213-7. doi: 10.1212/wnl.34.9.1213.
We studied a family with progressive dementia, optic atrophy, and spastic paraparesis. Autopsy of one family member revealed multisystem atrophy with widespread degeneration of the thalamus and marked attenuation of hemispheric white matter to account for the dementia. This family may suffer from a unique disorder, but the findings overlap with other reported cases of thalamic dementia or familial spastic paraparesis.
我们研究了一个患有进行性痴呆、视神经萎缩和痉挛性截瘫的家庭。对一名家庭成员进行尸检发现多系统萎缩，丘脑广泛变性，半球白质明显变薄，这可以解释痴呆的原因。这个家庭可能患有一种独特的疾病，但这些发现与其他已报道的丘脑痴呆或家族性痉挛性截瘫病例有重叠。
