Teo C G, Ting W C
Trans R Soc Trop Med Hyg. 1984;78(3):335-8. doi: 10.1016/0035-9203(84)90113-5.
An acquired bleeding syndrome associated with eosinophilia occurs in South-east Asia, mainly in children. Bleeding is known to result from impaired platelet function. This paper reports seven previously healthy young adults from Singapore who exhibited this syndrome. Bleeding was confined mainly to the skin and mucosal surfaces; no unusual clinical findings were noted. The bleeding tendency was transient. Intestinal helminths were found in four cases; five were mildly thrombocytopenic at onset. Platelet aggregation abnormalities were transient and the pattern suggested storage pool disease; this is discussed in relation to recent studies of the syndrome. The possible pathogenic role of eosinophilia and parasitism is also discussed.
一种与嗜酸性粒细胞增多相关的后天性出血综合征在东南亚出现，主要发生于儿童。已知出血是由血小板功能受损所致。本文报告了来自新加坡的7名此前健康的年轻人，他们表现出了这种综合征。出血主要局限于皮肤和黏膜表面；未发现异常临床体征。出血倾向是短暂的。4例发现肠道寄生虫；5例发病时轻度血小板减少。血小板聚集异常是短暂的，其模式提示为贮存池病；结合该综合征的近期研究对此进行了讨论。还讨论了嗜酸性粒细胞增多和寄生虫感染可能的致病作用。
