Phospholipids, vitamin A and ubiquinone of the Golgi apparatus subfractions from rat liver after acute ethanol intoxication.

Previous investigations from our laboratory have shown that during acute ethanol intoxication the Golgi apparatus seems involved in impaired dismission of lipoproteins. In the present paper the phospholipid distributions of Golgi subfractions have been analyzed in livers of normal and ethanol intoxicated rats. No significant differences in the phospholipid classes have been observed in this study. On the contrary, a decrease of vitamin A and ubiquinone in Golgi subfractions is evident. The results are briefly discussed in view of the role played by these endogenous antioxidants in the Golgi membranes and in the pathogenesis of ethanol induced fatty liver.