Krause W
Hautarzt. 1984 Jul;35(7):354-8.
Some methods for the separation of spermatozoa are described, with the aim of: 1. Increasing the "quality" of seminal parameters in subfertile men 2. Separating spermatozoa containing X and Y chromosomes 3. Deleting spermatozoa containing certain genetic information. Mainly gravimetric methods were used and concentration of motile spermatozoa was obtained, but the sperm density was always diminished. None of the methods used so far has been able to increase the fertility index or change the sex proportion of children born after artificial insemination.
描述了一些精子分离方法,目的如下:1. 提高亚生育男性精液参数的“质量”;2. 分离含有X和Y染色体的精子;3. 去除含有特定遗传信息的精子。主要使用了重量法并获得了活动精子的浓度,但精子密度总是降低。迄今为止所使用的方法均未能提高生育指数或改变人工授精后出生儿童的性别比例。