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芬兰分开抚养的双胞胎。II:同卵性、环境差异以及体重和身高的验证。

Finnish twins reared apart. II: Validation of zygosity, environmental dissimilarity and weight and height.

作者信息

Langinvainio H, Koskenvuo M, Kaprio J, Sistonen P

出版信息

Acta Genet Med Gemellol (Roma). 1984;33(2):251-8. doi: 10.1017/s0001566000007297.

DOI:10.1017/s0001566000007297
PMID:6540958
Abstract

Within the Finnish Twin Cohort of like-sexed adult twin pairs, a subgroup of pairs separated at an early age has been identified. In 165 pairs, both cotwins responded to questionnaires in 1975 and 1979. An environmental dissimilarity score was formed which consists of items on whether the twins had lived after separation in the same community, attended the same school, were on the same grade at school, how often the cotwins met, how often they met common friends and relatives and whether they attended the same clubs etc, or not. To validate the zygosity diagnosis obtained by questionnaire in 1975, those pairs whose zygosity was unknown as well as those with the least contact after separation were contacted for blood sampling (11 bloodgroups). Of 15 pairs with no zygosity diagnosis, 10 responded (1 no address,2 abroad,2 refused). Six pairs were classified MZ and 4 DZ. In 12 MZ and 8 DZ pairs undergoing bloodgroup determination, the classification of only one pair changed from DZ to MZ. The following intraclass correlations for height and weight were found.

摘要

在芬兰成年同性双胞胎队列中,已识别出一组早年分离的双胞胎亚组。在165对双胞胎中,两个双胞胎都在1975年和1979年对问卷进行了回复。形成了一个环境差异分数,该分数由关于双胞胎在分离后是否生活在同一社区、是否就读于同一所学校、在学校是否同年级、双胞胎见面的频率、他们与共同朋友和亲戚见面的频率以及他们是否参加同一俱乐部等项目组成。为了验证1975年通过问卷获得的合子性诊断,联系了那些合子性未知以及分离后联系最少的双胞胎进行血液采样(11种血型)。在15对未进行合子性诊断的双胞胎中,10对做出了回应(1对无地址,2对在国外,2对拒绝)。6对被分类为同卵双胞胎,4对为异卵双胞胎。在12对同卵双胞胎和8对异卵双胞胎进行血型测定时,只有1对的分类从异卵双胞胎变为同卵双胞胎。发现了以下身高和体重的组内相关性。

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