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遗传对血浆成分的影响:关于某些生化变量的双胞胎研究。

The effects of inheritance on constituents of plasma: a twin study on some biochemical variables.

作者信息

Whitfield J B, Martin N G

出版信息

Ann Clin Biochem. 1984 May;21 ( Pt 3):176-83. doi: 10.1177/000456328402100303.

Abstract

Heritability and within-person repeatability of thirteen constituents of plasma were assessed in a study of 206 pairs of male and female twins. Repeat measurements were available on 44 pairs. For bilirubin, calcium, creatinine, phosphate and potassium, the individuality of these characteristics was genetic in origin. Total protein, albumin and globulin showed significant heritability but considerable variation between occasions, while bicarbonate, chloride, iron, sodium and urea showed mainly environmental effects.

摘要

在一项对206对男性和女性双胞胎的研究中,评估了血浆中13种成分的遗传力和个体内重复性。44对双胞胎有重复测量数据。对于胆红素、钙、肌酐、磷酸盐和钾,这些特征的个体差异源于遗传。总蛋白、白蛋白和球蛋白显示出显著的遗传力,但不同测量之间存在相当大的差异,而碳酸氢盐、氯、铁、钠和尿素主要受环境影响。

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