Mathur N K, Sharma M, Mangal H N, Rai S M
Int J Lepr Other Mycobact Dis. 1984 Sep;52(3):327-30.
Serum zinc levels were estimated in 146 patients with different types of leprosy and 40 control subjects. Tuberculoid patients were found to have normal serum zinc levels. A gradual reduction in serum zinc levels was observed from TT to LL. Serum zinc levels were not significantly higher in patients treated with dapsone for approximately 18 months. The cause of hypozincemia is not clear, but the findings suggest that there are correlations among bacillary load, immune status, and serum zinc. Zinc deficiency could be one of the factors involved in the nonspecific suppression of cell-mediated immunity in lepromatous leprosy.
对146例不同类型麻风患者和40例对照者进行了血清锌水平测定。发现结核样型患者血清锌水平正常。从结核样型（TT）到瘤型（LL）观察到血清锌水平逐渐降低。接受氨苯砜治疗约18个月的患者血清锌水平没有显著升高。低锌血症的原因尚不清楚，但研究结果表明，细菌载量、免疫状态和血清锌之间存在相关性。锌缺乏可能是瘤型麻风患者细胞介导免疫非特异性抑制的相关因素之一。
