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Enterococcal superinfection and colonization with aztreonam therapy.

作者信息

Chandrasekar P H, Smith B R, LeFrock J L, Carr B

出版信息

Antimicrob Agents Chemother. 1984 Aug;26(2):280-2. doi: 10.1128/AAC.26.2.280.

Abstract

Patients were given aztreonam (SQ 26,776) parenterally for the treatment of various gram-negative infections. During or shortly after therapy, 8 (17.8%) of 45 patients became infected with or colonized by enterococcus. These eight cases included eight urinary tract isolates; one of these cases subsequently developed bacteremia. Five patients required further antimicrobial therapy directed against enterococcus. Patients receiving aztreonam are at risk for the development of enterococcal superinfection or colonization.

摘要

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本文引用的文献

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Pharmacokinetics of the monobactam SQ 26,776 after single intravenous doses in healthy subjects.
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