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用加速度计评估时,γ辐射会使大鼠的行为表现下降。

Gamma radiation produced performance decrement in rat as assessed with the accelerod.

作者信息

Cockerham L G, Bogo V, Gosset-Hagerman C J

出版信息

Neurosci Lett. 1984 Aug 31;49(3):297-300. doi: 10.1016/0304-3940(84)90305-7.

DOI:10.1016/0304-3940(84)90305-7
PMID:6541766
Abstract

Early transient incapacitation (ETI) and/or performance decrement (PD) is a reduction in performance during the first 30 min after exposure to a relatively high, rapidly delivered dose of ionizing radiation. The accelerod provides a sensitive measure of functional impairment in neurotoxic evaluations of chemical agents and demonstrates that the motor performance of gamma-radiation-exposed Sprague-Dawley rats was significantly different from that of sham-radiated controls.

摘要

早期短暂失能(ETI)和/或性能下降(PD)是指在暴露于相对高剂量、快速给予的电离辐射后的最初30分钟内性能下降。加速度计在化学制剂的神经毒性评估中提供了一种敏感的功能损害测量方法,并表明接受γ射线照射的Sprague-Dawley大鼠的运动性能与假照射对照组有显著差异。

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