Bogo V
Radiat Res. 1984 Nov;100(2):313-20.
Relatively high, rapidly delivered doses of ionizing radiation have been reported to produce an immediate decrement in performance (PD) in a number of animal species. This study investigated the effects of bremsstrahlung and electron radiation on the performance of rats unilaterally exposed by a linear accelerator (LINAC facility) at a midline tissue dose rate of 2000 rad/min. Relative radiation effects were determined by establishing median effective doses (ED50) for rats trained on the accelerod, which is a shock-avoidance test of motor performance. The ED50s were based on 10-min postexposure performance. Subjects were also tested at 15, 30, 60, and 120 min and 24 hr after exposure. Fifty-seven trained rats were exposed to bremsstrahlung radiation, and 40 trained rats were exposed to electrons. The ED50 was 8121 rad for the bremsstrahlung field and 6110 rad for the electron field, for a significantly different relative effectiveness of the electron field in producing PD of 1.35. The data imply that different radiation fields are not equally effective in producing PD.
据报道，相对高剂量、快速给予的电离辐射会使许多动物物种的行为表现立即下降（PD）。本研究调查了在直线加速器（LINAC设备）以2000拉德/分钟的中线组织剂量率单侧照射大鼠时，韧致辐射和电子辐射对其行为表现的影响。通过确定在加速度计上训练的大鼠的半数有效剂量（ED50）来确定相对辐射效应，加速度计是一种对运动行为表现的避震测试。ED50基于照射后10分钟的行为表现。还在照射后15、30、60和120分钟以及24小时对实验对象进行测试。57只经过训练的大鼠接受了韧致辐射，40只经过训练的大鼠接受了电子辐射。韧致辐射场的ED50为8121拉德，电子辐射场的ED50为6110拉德，电子场在产生行为表现下降方面的相对有效性显著不同，为1.35。数据表明，不同的辐射场在产生行为表现下降方面的效果并不相同。
