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[冯·希佩尔病视网膜毛细血管瘤的治疗]

[Treatment of retinal capillary angiomas of von Hippel's disease].

作者信息

Bonnet M, Garmier G

出版信息

J Fr Ophtalmol. 1984;7(8-9):545-55.

PMID:6542923
Abstract

Twelve patients with Von Hippel's disease were observed by the authors during the last decade. 4 patients developed new retinal or papillary angiomas during the follow-up period (1 to 10 years with an average of 4,5 years). 55 retinal capillary angiomas and 2 papillary angiomas were observed in the present series. All retinal angiomas were submitted to treatment. Cryotreatment under biomicroscopic control of the fundus was applied on 11 angiomas, argon laser photocoagulation was applied on 36 angiomas, and 8 angiomas were treated with both techniques. Clinical destruction of the angiomas and normalization of the feeder vessels caliber were achieved in all cases. At the end of the follow-up period the visual acuity was the same or better in 16 of the 17 treated eyes; the visual acuity was worse in 1 eye. The smaller the retinal angioma the easier, the more efficient and the less mutilating the treatment is. Therefore the patients should be followed up at regular intervals in order to treat incipient lesions rather than large tumors.

摘要

在过去十年中,作者观察了12例冯·希佩尔病患者。4例患者在随访期间(1至10年,平均4.5年)出现了新的视网膜或视乳头血管瘤。本系列观察到55个视网膜毛细血管瘤和2个视乳头血管瘤。所有视网膜血管瘤均接受了治疗。在眼底生物显微镜控制下对11个血管瘤进行了冷冻治疗,对36个血管瘤进行了氩激光光凝治疗,8个血管瘤采用了两种技术治疗。所有病例均实现了血管瘤的临床破坏和供血血管管径的正常化。随访期末,17只接受治疗的眼中有16只视力相同或更好;1只眼视力下降。视网膜血管瘤越小,治疗越容易、越有效且致残性越小。因此,应定期对患者进行随访,以便治疗早期病变而非大肿瘤。

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