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[大鼠背侧和腹侧海马在防御行为中的功能作用]

[Functional role of the dorsal and ventral hippocampus in defensive behavior in the rat].

作者信息

Chaĭchenko G M

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1984 Nov-Dec;34(6):1109-15.

PMID:6543074
Abstract

Bilateral electrolytic lesions of the dorsal hippocampus of white rats were shown to facilitate elaboration of a conditioned response of active avoidance of pain shock in a shuttle-box. The lesions of the ventral hippocampus had no effect on conditioning. The ventral hippocampal lesions led to a complete failure to form differential inhibition. In rats with the dorsal hippocampal lesions an acquisition of partial (up to 60 per cent) discrimination of stimuli was possible. The differences in avoidance conditioning and elaboration of differential inhibition in rats with the dorsal and ventral hippocampal lesions are supposed to be caused by the changes of general excitability and emotional state of animals as well as by a specific role of the ventral hippocampus in memory consolidation.

摘要

实验表明,对白鼠双侧背侧海马进行电解损伤,有助于在穿梭箱中建立主动回避疼痛电击的条件反应。腹侧海马损伤对条件作用没有影响。腹侧海马损伤导致完全无法形成分化抑制。在背侧海马损伤的大鼠中,有可能获得部分(高达60%)的刺激辨别能力。背侧和腹侧海马损伤的大鼠在回避条件作用和分化抑制形成方面的差异,被认为是由动物的一般兴奋性和情绪状态的变化以及腹侧海马在记忆巩固中的特定作用引起的。

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[Functional role of the dorsal and ventral hippocampus in defensive behavior in the rat].[大鼠背侧和腹侧海马在防御行为中的功能作用]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1984 Nov-Dec;34(6):1109-15.
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[Effect of destruction of the septum and hippocampus on the shuttle-box avoidance conditioning of the rat].[中隔与海马损毁对大鼠穿梭箱回避条件反射的影响]
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Neurobiol Learn Mem. 2004 May;81(3):172-84. doi: 10.1016/j.nlm.2004.02.005.
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Differential contributions of dorsal vs. ventral hippocampus to auditory trace fear conditioning.背侧海马与腹侧海马在听觉痕迹恐惧条件反射中的不同作用。
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[Effect of destruction of the basolateral portion and medial nuclei of the amygdaloid complex on defensive conditioned reflexes in rats].[杏仁复合体基底外侧部和内侧核破坏对大鼠防御性条件反射的影响]
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[Correlation between the retention of defensive conditioned reflexes and rat brain acetylcholinesterase activity].[防御性条件反射的保持与大鼠脑乙酰胆碱酯酶活性之间的相关性]
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