新型11-取代5H-二苯并[b,e][1,4]二氮䓬类化合物的合成及其神经学作用
[Synthesis and neurologic action of new 11-substituted 5H-dibenzo[b,e][1,4]diazepines].
作者信息
Skoldinov A P, Rayevskii K S, Likhosherstov A M, Stavrovskaja A W, Rüger C, Rostock A, Röhnert H
出版信息
Pharmazie. 1984 Dec;39(12):812-3.
PMID:6543394
Abstract
The synthesis of the title compounds is described. The compounds are characterized by having no cataleptogenic effect and no antagonistic effect against amphetamine stereotypies in experimental animals. The pharmacological results of the rota-rod, spontaneous motility, aggression-test, hexobarbital-potentiation and antagonism to physostigmine are reported.
摘要
本文描述了标题化合物的合成。这些化合物的特征在于在实验动物中没有致僵作用，并且对苯丙胺刻板行为没有拮抗作用。报告了转棒试验、自发运动、攻击试验、戊巴比妥增强作用以及对毒扁豆碱拮抗作用的药理学结果。
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