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[钍造影剂所致肺癌——关于钍造影剂应用后及陈旧性枪伤后癌发生的研究(作者译)]

[Thorotrast carcinoma of the lung--contribution to the genesis of carcinoma after application of thorotrast and of old bullet wound (author's transl)].

作者信息

Buchholz A

出版信息

Z Erkr Atmungsorgane. 1978 Jan;150(1):76-89.

PMID:654346
Abstract

A bronchogenic carcinoma was found in the sphere of the scar in a fifty-years-old man who suffered in 1945, 27 years before his death, from a pulmonary bullet wound caused by war influence. The histological examination furthermore disclosed considerable autoradiographic secured deposits of thorotrast in the carcinoma and scar sphere. One may suppose that in connection with the treatment of the results of this injury a bronchography or a preparation of the fistula followed. All available cases of a beginning of carcinoma after a pulmonary bullet wound as well as all cases of carcinoma of the lungs after thorotrast incorporation found in literature were collected, critically sorted out and represented in schedules. A summary of questions of the causes and pathogenesis is given.

摘要

在一名50岁男性的瘢痕区域发现了支气管源性癌。该男子于1945年,即其去世前27年,因战争影响遭受了肺部枪伤。组织学检查还显示,在癌组织和瘢痕区域有大量经放射自显影证实的钍造影剂沉积。可以推测,针对该损伤的治疗可能进行了支气管造影或瘘管准备。收集了文献中所有肺部枪伤后发生癌的起始病例以及所有钍造影剂注入后发生肺癌的病例,进行了严格筛选并制成表格呈现。文中还对病因和发病机制的问题进行了总结。

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