Bollag U, Albrecht E, Wingert W
Helv Paediatr Acta. 1984 Oct;39(4):341-5.
Seventy-four children from three weeks to two years of age with various upper respiratory symptoms were randomly assigned to three groups: two intervention groups (saline nose drops; medicated nose drops) and a control group (no nose drops). Forty-six children returned for check-up two days later. Subjects in all three groups improved between first and second contact. There was no significant difference between the three groups. It is concluded that medicated nose drops are not essential in the treatment of upper respiratory infection and rhinitis.
74名年龄在3周至2岁之间、有各种上呼吸道症状的儿童被随机分为三组：两个干预组（生理盐水滴鼻剂；含药滴鼻剂）和一个对照组（不使用滴鼻剂）。46名儿童在两天后返回接受检查。所有三组的受试者在首次和第二次接触之间都有改善。三组之间没有显著差异。得出的结论是，含药滴鼻剂对上呼吸道感染和鼻炎的治疗并非必不可少。
