Patel R I, Oh T H, Chandra R, Epstein B S
Anaesthesia. 1984 Sep;39(9):862-4. doi: 10.1111/j.1365-2044.1984.tb06570.x.
The volume and pressure of a tracheal tube cuff inflated with air increases during nitrous oxide anaesthesia. The study was designed to investigate the changes of tracheal tube cuff pressure during nitrous oxide anaesthesia following inflation of the cuff with air or saline in 10 mongrel dogs who were anaesthetised with nitrous oxide and their lungs artificially ventilated. At the end of 6 hours there was no change in cuff pressure when saline had been used for inflation, but was six times the initial pressure when air had been used. On microscopic examination of the trachea, only the air group had glandular inflammation, dilatation and destruction. Therefore, it appears that if saline is used to inflate tracheal tube cuffs, there will not be an increase in cuff volume and pressure during nitrous oxide anaesthesia.
在氧化亚氮麻醉期间，用空气充气的气管导管套囊的容积和压力会增加。本研究旨在调查10只杂种犬在氧化亚氮麻醉且肺部人工通气的情况下，用空气或生理盐水给气管导管套囊充气后，套囊压力在氧化亚氮麻醉期间的变化。6小时结束时，使用生理盐水充气时套囊压力无变化，但使用空气充气时套囊压力是初始压力的6倍。在对气管进行显微镜检查时，只有空气组出现了腺体炎症、扩张和破坏。因此，似乎如果使用生理盐水给气管导管套囊充气，在氧化亚氮麻醉期间套囊容积和压力不会增加。
