Forni E, Zadra F, Spelzini P, Lo Monaco G, Bordoni P, Clerico D
Chir Ital. 1984 Oct;36(5):807-18.
During the period between november 1964 and december 1982, 48 patients were operated upon for metastatic lesions of lung from previous or actual carcinomas and sarcomas elsewhere in the body. The most frequent sites of origin of the primary malignancy were colon, testis and breast. The usual approach was through a thoracotomy; bilateral lung metastases were removed with one-stage procedure through a median sternotomy in two patients. The operative mortality was 2%. Overall five-year survival was 26%, which was not influenced by tumor histology, disease-free interval, or extent of pulmonary excision. In view of these findings, conservative pulmonary resection of metastatic lesions is advocated, regardless of the tumor histology or the disease-free interval, when the following criteria are adhered to: primary site controlled or controllable; no extrapulmonary metastases demonstrable; good operative risk; no other effective means of treatment available.
在1964年11月至1982年12月期间，48例患者因身体其他部位先前或实际存在的癌和肉瘤的肺转移灶而接受手术。原发性恶性肿瘤最常见的起源部位是结肠、睾丸和乳腺。通常的手术方法是开胸手术；两名患者通过正中胸骨切开术一期切除双侧肺转移灶。手术死亡率为2%。总体五年生存率为26%，不受肿瘤组织学、无病间期或肺切除范围的影响。鉴于这些发现，当符合以下标准时，无论肿瘤组织学或无病间期如何，均主张对转移灶进行保守性肺切除：原发部位已得到控制或可控制；无明显肺外转移；手术风险良好；没有其他有效的治疗手段。
