Benezra D, Gery I, Chan C C, Nussen-Blatt R B, Palestine A G, Kaiser-Kupfer M, Maftzir G, Peer J
Ophthalmic Paediatr Genet. 1984 Dec;4(3):193-7. doi: 10.3109/13816818409006121.
Patients with retinitis pigmentosa, other retinal degenerations and a group of normal volunteers were included in a masked study designed to examine the existence of autoimmune reactions toward retinal antigens and the possible defect in lymphokine production (IL-1, IL-2 and gamma interferon). The results obtained did not show any specific anamnestic response to the retinal S-Ag nor any outstanding defect in gamma interferon production by the lymphocytes of patients with retinitis pigmentosa. It is suggested that a larger masked study be conducted as soon as possible in order to clarify these aspects of immune aberrations in patients with retinitis pigmentosa.
患有色素性视网膜炎、其他视网膜变性的患者以及一组正常志愿者被纳入一项盲法研究，该研究旨在检测针对视网膜抗原的自身免疫反应的存在情况以及淋巴因子产生（白细胞介素-1、白细胞介素-2和γ干扰素）可能存在的缺陷。所获得的结果未显示对视网膜S抗原存在任何特异性回忆反应，也未显示色素性视网膜炎患者淋巴细胞产生γ干扰素存在任何显著缺陷。建议尽快进行规模更大的盲法研究，以阐明色素性视网膜炎患者免疫异常的这些方面。
