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子宫颈癌患者的维生素B6状况

Vitamin B6 status in patients with cancer of the uterine cervix.

作者信息

Ramaswamy P G, Natarajan R

出版信息

Nutr Cancer. 1984;6(3):176-80. doi: 10.1080/01635588509513821.

DOI:10.1080/01635588509513821
PMID:6545576
Abstract

The activities of aspartate aminotransferase and alanine aminotransferase in erythrocytes with and without the addition of pyridoxal phosphate were determined in healthy controls and in Indian women with cancer of the uterine cervix. The percent stimulation of the erythrocyte transferases as a result of the addition of pyridoxal phosphate was negligible in the case of normal subjects (less than 5% stimulation). In the patients with cervical cancer, a 23-35% stimulation was observed, indicating a deficiency of vitamin B6. It is not yet known whether the deficiency is the cause of the disease or due to the tumor.

摘要

在健康对照组和患有宫颈癌的印度女性中,测定了添加和未添加磷酸吡哆醛的红细胞中天冬氨酸转氨酶和丙氨酸转氨酶的活性。对于正常受试者,添加磷酸吡哆醛后红细胞转氨酶的刺激百分比可忽略不计(刺激小于5%)。在宫颈癌患者中,观察到刺激率为23%-35%,表明维生素B6缺乏。目前尚不清楚这种缺乏是疾病的原因还是由肿瘤引起的。

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