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[丘脑背内侧核刺激对皮质电活动同步流的影响]

[Effect of stimulation of the mediodorsal nucleus of the thalamus on the synchronous flow of cortical electrical processes].

作者信息

Ignat'ev D A, Muradova I O

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1978 Mar-Apr;28(2):387-93.

PMID:654579
Abstract

It was shown in chronic experiments on rabbits that stimulation of the mediodorsal thalamic nucleus brings about, as a rule, en enhancement of amplitudes of the spatially-synchronous cortical theta-rhythm and a decreased frequency of its oscillations. Analysis of the phenomenon by means of a simple mathematical models shows that such a connection between amplitude and frequency EEG parameters may be accounted for by the existence of two-way cyclic interactions between the cortex and the thalamus, forming a closed contour of a feedback connection. The capacity of the mediodorsal thalamic nucleus to influence the synchroneity of cortical electrical processes is compared with published data on its role in conditioned activity.

摘要

在对兔子的慢性实验中发现,通常情况下,刺激丘脑背内侧核会导致空间同步皮层θ节律的振幅增强,其振荡频率降低。通过简单数学模型对该现象进行分析表明,脑电图参数的振幅与频率之间的这种联系可能是由于皮层与丘脑之间存在双向循环相互作用,形成了反馈连接的封闭回路。将丘脑背内侧核对皮层电活动同步性的影响能力与已发表的关于其在条件活动中作用的数据进行了比较。

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