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自发性高血压大鼠（SHR）肾、肠系膜和后肢血管床中去甲肾上腺素的血管运动逃逸

Vasomotor escape from noradrenaline in the renal, mesenteric and hindquarter vascular beds in spontaneously hypertensive rats (SHR).

作者信息

Wróblewski T E, Grójec M

出版信息

Acta Physiol Pol. 1984 Jul-Aug;35(4):324-9.

PMID:6545926
Abstract

During 10 minutes of infusion of noradrenaline in doses of 0.1, 0.2, 0.4 and 0.6 micrograms/min into isolated intestinal, kidney and hindquartet preparation, perfused with aerated Tyrode's solution and escape effect was observed in normotensive rats. The escape was significantly reduced in intestinal and renal vascular beds or disappeared in spontaneously hypertensive rats.

摘要

在向用充氧台氏液灌注的离体肠、肾和后肢标本中以0.1、0.2、0.4和0.6微克/分钟的剂量输注去甲肾上腺素10分钟的过程中，在血压正常的大鼠中观察到了逃逸效应。在自发性高血压大鼠中，肠和肾血管床的逃逸效应显著降低或消失。

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