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治疗性高压环境后发生的致命减压病(作者译)

[Fatal decompression sickness following therapeutic hyperbaric environment (author's transl)].

作者信息

Richter K, Löblich H J

出版信息

Z Rechtsmed. 1978 Mar 28;81(1):45-61. doi: 10.1007/BF00200598.

DOI:10.1007/BF00200598
PMID:654597
Abstract

In Hannover/Germany in 1976 a so called "Society for Regenerative Hyperbaric Therapy" (Gesellschaft für Regenerative Uberdruck-Therapie) subjected 20 patients within two coupled multi-place chambers to a simulated hyperbaric environment, equivalent to a maximum of 4 ata, followed usually by gradual reductions of the pressure. The patients were of an average age of 67.2 years and were afflicted by various disorders. During one of the "dives" a patient developed air embolism of the central nervous system. During ensuing confusion of the chamber was opened suddenly, with resultant explosive reduction of the high pressure. This resulted in five letal accidents of decompression sickness. Post mortem examination revealed diffuse distribution of gas bubbles throughout the entire body. By elecronmicroscopy each bubble was covered by an osmiophilic coat. Post mortem findings are discussed and correlated with well-known and new clinical symptomes. These observations present for the first time fatal accidents of decompression sickness in humans, associated with hyperbaric air-therapy.

摘要

1976年在德国汉诺威,一个所谓的“再生高压疗法协会”让20名患者在两个相连的多人舱内接受模拟高压环境,最高相当于4个绝对大气压,随后通常逐渐减压。患者平均年龄67.2岁,患有各种疾病。在一次“潜水”过程中,一名患者发生了中枢神经系统空气栓塞。在随后的混乱中,舱门突然打开,导致高压急剧下降。这造成了5例减压病致死事故。尸检发现全身有气泡弥漫分布。通过电子显微镜观察,每个气泡都被一层嗜锇膜覆盖。对尸检结果进行了讨论,并与已知和新出现的临床症状相关联。这些观察首次呈现了与高压空气疗法相关的人类减压病致死事故。

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引用本文的文献

1
Ultrastructural aspects of bubble formation in human fatal accidents after exposure to compressed air.
Virchows Arch A Pathol Anat Histol. 1978 Nov 14;380(3):261-71. doi: 10.1007/BF00430462.

本文引用的文献

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