Lauckner W, Schwarz R, Retzke U
Zentralbl Gynakol. 1978;100(4):217-21.
10 late pregnant women with hypotension were examined before and after the intravenous injection of 30 mg mephentermin with the method of quantitative sphygmometry, the bloodless graphic registration of the arterial blood pressure and direct electronic timing of pulse wave velocity. Systolic and diastolic blood pressure increase significantly. The cause of this rise in arterial blood pressure is the increase of stroke volume exclusively. Heart rate and total peripheral resistance remain constant. This hemodynamic mode of action is a favourable one in regard to protection of uteroplacental blood flow. Therefore mephentermin is suitable for treatment of hypotension in pregnancy.
对10名晚期妊娠低血压妇女，采用定量血压测量法、动脉血压无血图形记录法和脉搏波速度直接电子计时法，在静脉注射30毫克美芬丁胺前后进行了检查。收缩压和舒张压显著升高。动脉血压升高的原因仅是每搏输出量增加。心率和总外周阻力保持不变。这种血液动力学作用方式对保护子宫胎盘血流是有利的。因此，美芬丁胺适用于治疗妊娠低血压。
