Retzke U, Schwarz R, Lauckner W, During R
Zentralbl Gynakol. 1979;101(16):1034-8.
Dilatol (Nylidrin), a betamimetic used for tocolysis, was applied to ten hypertensive women in advanced pregnancy and produced in them characteristic effects with favourable impact upon oxygen supply to the foetuses, such as significant lowering of diastolic pressure, decrease in total peripheral resistance which reflected increase in uteroplacental blood flow, as well as rises in heart rate, stroke volume, and cardiac output. Nylidrin, therefore, may be recommended as a hypotensive drug in the treatment of arterial hypertension in pregnancy.
利托托(尼立替林)是一种用于安胎的β受体激动剂,应用于10名晚期妊娠的高血压女性患者,产生了特征性效果,对胎儿的氧气供应有有利影响,如舒张压显著降低、总外周阻力降低,这反映了子宫胎盘血流量增加,同时心率、每搏输出量和心输出量也有所增加。因此,尼立替林可作为治疗妊娠高血压的降压药物推荐使用。