Bert J L, Pinder K L
Microvasc Res. 1984 Jan;27(1):51-70. doi: 10.1016/0026-2862(84)90041-4.
An analog computer simulation of human pulmonary microvascular exchange was programmed and tested. This model of blood-to-lymph transport is based on a compartmental analysis of the lungs and has the capacity to describe fluid volumes, plasma protein content, flows and pressures for both normal and perturbed conditions. Normal conditions were predicted and shown to be in agreement with the literature. The trends in the response of the lungs to changes in microvascular pressure is shown also to agree with the literature both for steady state and transient predictions. The results of a sensitivity analysis, which demonstrates the response of the lungs to a variety of perturbations, is also reported. The simulation predicts reasonable results for normal, transient, and perturbed conditions in human lungs.
对人体肺微血管交换进行了模拟计算机仿真并进行了测试。这种血液到淋巴液转运的模型基于肺部的房室分析，能够描述正常和异常情况下的液体容量、血浆蛋白含量、流量和压力。预测了正常情况，并表明与文献一致。肺部对微血管压力变化的反应趋势在稳态和瞬态预测方面也与文献一致。还报告了敏感性分析的结果，该分析展示了肺部对各种干扰的反应。该模拟对人体肺部正常、瞬态和异常情况下的预测结果合理。
