Hakim-Elahi A
J Hered. 1984 Mar-Apr;75(2):150-1. doi: 10.1093/oxfordjournals.jhered.a109895.
A FORTRAN computer program was developed to calculate recombination values from F2 data. The input to the program is data on codominant alleles in any number of F2 families segregating for any number of loci, the limit being applied by the computer's memory capacity. For each pair of loci, regardless of the number of segregating progenies used, one recombination value is estimated by the method of maximum likelihood and reported with its standard error. In cases in which more than one family is used for the estimation, the chi-square for the homogeneity of the data also is reported.
开发了一个FORTRAN计算机程序,用于根据F2数据计算重组值。该程序的输入是任意数量的F2家系中任何数量基因座的共显性等位基因数据,限制条件由计算机的内存容量决定。对于每一对基因座,无论使用的分离后代数量如何,都通过最大似然法估计一个重组值,并报告其标准误差。在使用多个家系进行估计的情况下,还会报告数据同质性的卡方值。