Löhrke H, Hesse B, Goerttler K
Exp Pathol. 1984;25(1):57-63. doi: 10.1016/s0232-1513(84)80008-0.
A spontaneously occurring lymphosarcoma of the Syrian golden hamster was both subcutaneously and intravenously inoculated into 300 female and male animals each. Tumor growth was observed at a 100% rate. Using both types of inoculations, metastases occurred in 50% of the inoculated animals, preferentially in lungs, liver, pancreatic lymph nodes, spleen and kidney. The participation of different lymph node groups was more frequent after subcutaneous application. The transplantable tumor described might serve as a mode for additional studies on experimentally induced metastasis.
将一只自发产生的叙利亚金仓鼠淋巴肉瘤分别皮下和静脉接种到300只雌性和雄性动物体内。观察到肿瘤生长率为100%。使用这两种接种方式，50%的接种动物发生了转移，转移部位主要在肺、肝、胰淋巴结、脾和肾。皮下接种后不同淋巴结组的参与更为频繁。所描述的可移植肿瘤可作为进一步研究实验性诱导转移的模型。
