Utin A V
Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(4):580-2.
A clinico-genealogical study revealed an increased (in 2--3 times) frequency of allergies in epileptic patients and their close relatives (291 families) in comparison with a general population (118 families). Risk for appearance of epilepsy and children's convulsions among the sibs of the probands with parental allergic loading occurred to be 2 times higher than without it. It is established that parental allergic loading and its degree is one of a family-constitutional risk factors that significantly raises the frequency of a phenotypical manifestation of hereditary predisposition to epilepsy and children's convulsions.
一项临床系谱研究表明，与普通人群（118个家庭）相比，癫痫患者及其近亲（291个家庭）中过敏症的发生率增加了（2至3倍）。在先证者的同胞中，父母有过敏负荷时出现癫痫和儿童惊厥的风险比没有过敏负荷时高2倍。已确定父母的过敏负荷及其程度是家族体质性风险因素之一，可显著提高癫痫和儿童惊厥遗传易感性表型表现的发生率。
