Utin A V
Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(8):1226-31.
A comparative clinico-constitutional analysis of 73 cases of epilepsy with an identical parental loading and 179 without it, demonstrated that the degree and character of a parental loading is one of the genotypical factors determining the fenotypical polymorphism of epilepsy. This circumstances causes the frequency of associations with dysgenesia, epileptoid traits, modifying the age of manifestation and progression of the disease. This should also be taken into consideration in prognosticating the severity of epilepsy during treatment and socio-labor adaptation in patients depending upon the degree and character of identical parental loading.
对73例有相同亲本负荷的癫痫病例和179例无相同亲本负荷的癫痫病例进行的临床体质比较分析表明,亲本负荷的程度和特征是决定癫痫表型多态性的基因型因素之一。这种情况导致与发育异常、类癫痫特征的关联频率,改变了疾病的表现年龄和进展。在根据相同亲本负荷的程度和特征对患者治疗期间癫痫的严重程度以及社会劳动适应情况进行预后评估时,也应考虑到这一点。