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通过将日本鮟鱇(Lophius litulon)的血浆与斯坦尼斯小体一起孵育形成的血管紧张素的化学结构。

Chemical structure of angiotensin formed by incubating plasma with the corpuscles of Stannius in the Japanese goosefish, Lophius litulon.

作者信息

Hasegawa Y, Watanabe T X, Nakajima T, Sokabe H

出版信息

Gen Comp Endocrinol. 1984 May;54(2):264-9. doi: 10.1016/0016-6480(84)90180-1.

Abstract

The chemical structure of angiotensin formed by incubating the extract of the corpuscles of Stannius (CS) with homologous plasma in the Japanese goosefish , Lophius litulon , was analyzed. Goosefish CS angiotensin was proposed as [Asn1, Val5, His9 ] angiotensin I based on amino acid analysis and fluorescent peptide mapping techniques. It had the same structure as angiotensin produced by incubating the kidney extract with homologous plasma, indicating that CS angiotensin was not organ specific.

摘要

分析了在日本鮟鱇(Lophius litulon)中,将斯坦尼斯小体(CS)提取物与同源血浆一起孵育形成的血管紧张素的化学结构。基于氨基酸分析和荧光肽图谱技术,鮟鱇CS血管紧张素被认定为[天冬酰胺1、缬氨酸5、组氨酸9]血管紧张素I。它与将肾脏提取物与同源血浆一起孵育产生的血管紧张素结构相同,这表明CS血管紧张素并非器官特异性的。

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