Landier F, Chaussain J L, Job J C
Arch Fr Pediatr. 1984 Mar;41(3):163-6.
Of 15 neonates born to mothers presenting with Graves' disease, who were admitted for presumptive thyroid disorder, 6 presented with neonatal thyrotoxicosis, 4 with goiter and/or hypothyroidism, and 5 presented with euthyroidism. In cases with thyrotoxicosis, the mothers were not or insufficiently treated. Evolution was regressive in 5 instances, there was a craniostenosis and persisting hyperthyroidism in one case. In cases with goiter and/or hypothyroidism, on the other hand, the mothers were correctly treated, and neonatal manifestations were benign and transient. This emphasizes both the importance of supervising gravidic hyperthyroidism and the complexity of materno-foetal relationship in thyroid diseases.
在因疑似甲状腺疾病入院的15名患有格雷夫斯病母亲所生的新生儿中,6名出现新生儿甲状腺毒症,4名出现甲状腺肿和/或甲状腺功能减退,5名甲状腺功能正常。在甲状腺毒症病例中,母亲未接受治疗或治疗不充分。5例病情呈退行性发展,1例出现颅骨狭窄并持续存在甲状腺功能亢进。另一方面,在甲状腺肿和/或甲状腺功能减退的病例中,母亲得到了正确治疗,新生儿的表现为良性且短暂。这既强调了监测妊娠甲亢的重要性,也凸显了甲状腺疾病中母婴关系的复杂性。