Francis R J
Comput Programs Biomed. 1984 Feb-Apr;18(1-2):43-9. doi: 10.1016/0010-468x(84)90022-9.
A new program ELSMOS has been developed for curve fitting of pharmacokinetic and pharmacodynamic data. The form is sufficiently general, with user-defined model in a separate FORTRAN subroutine, to permit application in many other areas. The principal features are the use of a user-defined error model for statistically rigorous automatic weighting of data, and the containment of program size to a level that enables mini- or micro-computer implementation.
已开发出一个名为ELSMOS的新程序,用于药代动力学和药效学数据的曲线拟合。该程序形式足够通用,在一个单独的FORTRAN子程序中有用户定义模型,从而允许在许多其他领域应用。其主要特点是使用用户定义的误差模型对数据进行统计严格的自动加权,并且将程序规模控制在能够在小型或微型计算机上实现的水平。