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[头孢菌素过敏与头孢菌素-青霉素交叉过敏,特别涉及严重过敏反应的性病治疗]

[Cephalosporin allergy and cephalosporin-penicillin cross allergies with special reference to venereologic therapy of severe anaphylactic reactions].

作者信息

Korting H C

出版信息

Hautarzt. 1984 May;35(5):225-9.

PMID:6547704
Abstract

The newer cephalosporins are gaining more and more importance in antimicrobial chemotherapy. This also applies to venereology. Yet before widespread use, their potential for anaphylactic reactions must be defined, as they are not uncommon with penicillin. In fact, the first cephalosporins shared this drawback with penicillin. According to the experimental and clinical data available, the newer cephalosporins, however, should not give rise to severe allergic reactions of the immediate type. This at least holds true for individuals without a history of allergy to beta-lactam-antibiotics but, in fact, not even they should be endangered. This, however, still needs further confirmation.

摘要

新型头孢菌素在抗微生物化疗中越来越重要。这在性病学中也同样适用。然而,在广泛使用之前,必须明确它们引发过敏反应的可能性,因为青霉素引发过敏反应的情况并不罕见。事实上,第一代头孢菌素与青霉素有同样的缺点。根据现有的实验和临床数据,新型头孢菌素不应引发即刻型严重过敏反应。至少对于没有β-内酰胺类抗生素过敏史的个体来说是这样,但实际上,即使是他们也并非绝对安全。不过,这仍需进一步证实。

相似文献

1
[Cephalosporin allergy and cephalosporin-penicillin cross allergies with special reference to venereologic therapy of severe anaphylactic reactions].[头孢菌素过敏与头孢菌素-青霉素交叉过敏,特别涉及严重过敏反应的性病治疗]
Hautarzt. 1984 May;35(5):225-9.
2
Immediate allergic reactions to cephalosporins: evaluation of cross-reactivity with a panel of penicillins and cephalosporins.头孢菌素类药物的速发型过敏反应:与一组青霉素类和头孢菌素类药物交叉反应性的评估
J Allergy Clin Immunol. 2006 Feb;117(2):404-10. doi: 10.1016/j.jaci.2005.10.032.
3
Cephalosporin allergy.头孢菌素过敏。
N Engl J Med. 2002 Jan 31;346(5):380-1.
4
Risk of administering cephalosporin antibiotics to patients with histories of penicillin allergy.对有青霉素过敏史的患者使用头孢菌素类抗生素的风险。
Ann Allergy Asthma Immunol. 1995 Feb;74(2):167-70.
5
Immediate allergic reactions to cephalosporins and penicillins and their cross-reactivity in children.儿童对头孢菌素和青霉素的速发型过敏反应及其交叉反应性
Pediatr Allergy Immunol. 2005 Jun;16(4):341-7. doi: 10.1111/j.1399-3038.2005.00280.x.
6
Cephalosporin allergy.头孢菌素过敏
Immunol Allergy Clin North Am. 2004 Aug;24(3):463-76, vi-vii. doi: 10.1016/j.iac.2004.03.009.
7
[Hypersensitivity reactions due to penicillin and cephalosporin antibiotics].[青霉素和头孢菌素类抗生素引起的超敏反应]
Hautarzt. 1972 May;23(5):207-9.
8
Investigations on group allergy reactions to cefazedone in patients with penicillin allergy of the anaphylactic type (type I) and of the delayed type (type IV).
Arzneimittelforschung. 1979;29(2a):461-2.
9
Is there cross-reactivity between penicillins and cephalosporins?青霉素和头孢菌素之间存在交叉反应吗?
Am J Med. 2006 Apr;119(4):354.e11-9. doi: 10.1016/j.amjmed.2005.10.052.
10
Evaluation of immediate allergic reactions to cephalosporins in non-penicillin-allergic patients.非青霉素过敏患者中头孢菌素类药物即刻过敏反应的评估。
Int Arch Allergy Immunol. 2009;150(3):205-9. doi: 10.1159/000222672. Epub 2009 Jun 3.

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