Vilkov G A, Bardakhch'ian E A, Stepanenko E M, Siletskiĭ O Ia
Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(5):767-70.
Using electron microscopic and biochemical studies, the rat brain was examined following the intracisternal administration of IgG obtained from schizophrenics' blood serum. The resultant ultrastructural impairments of the sensorimotor cortex and activation of lipid peroxidation processes were similar to the alterations detected in the brain of the schizophrenic patients. The results suggest that the circulating cerebral antibodies in schizophrenics possess a membranotropic effect and may induce various structural and functional disorders in the central nervous system of these patients.
利用电子显微镜和生化研究方法，对经脑池内注射取自精神分裂症患者血清的IgG后的大鼠脑进行了检查。感觉运动皮层由此产生的超微结构损伤以及脂质过氧化过程的激活与在精神分裂症患者脑中检测到的改变相似。结果表明，精神分裂症患者体内循环的脑抗体具有膜otropic效应，并可能在这些患者的中枢神经系统中诱发各种结构和功能障碍。 （注：原文中“membranotropic”这个词可能有误，推测可能是“membrane - damaging”之类的词，这里按原文翻译）
