Amaral A L, Nascimento A G, Goellner J R
Arch Pathol Lab Med. 1984 Oct;108(10):808-10.
We examined two cases of proliferating pilar cysts of the inguinal region. One of the cases showed a transformation to epidermoid carcinoma and, despite surgical resection, the patient died by means of distant generalized metastases. The diagnosis of proliferating pilar cyst should be made in pilar cysts with epithelial proliferation that shows well-defined borders and abundant keratinization despite cytologic atypia and mitotic activity. The diagnosis of carcinoma in proliferating pilar cysts should be reserved for lesions showing poorly defined borders and clear-cut infiltrative properties with cytologic evidence of malignancy.
我们检查了两例腹股沟区的增殖性毛囊囊肿。其中一例发生了向表皮样癌的转变，尽管进行了手术切除，但患者因远处广泛转移而死亡。增殖性毛囊囊肿的诊断应基于具有上皮增生的毛囊囊肿，其边界清晰且有丰富的角化，尽管存在细胞异型性和有丝分裂活性。增殖性毛囊囊肿中癌的诊断应仅限于那些边界不清、具有明确浸润性且有细胞学恶性证据的病变。
