Bloch P H, Müller H D
Hautarzt. 1979 Feb;30(2):84-8.
The pilar tumor occurs mainly in elderly women. It is a solitary lesion, localized on the scalp in most cases. In spite of the usually long course of the disease, pilar tumors very rarely metastasize. Small tumors look like "sebaceous cysts", large and very large tumors are diagnosed as squamous cell carcinomas. In these cases one could directly come to the right diagnosis if sex, age and localization do correspond. Microscopic examination reveals interlacing lobules of squamous eqithelium that undergo in their center abrupt keratinization of pilar or trichilemmal cysts. The pilar tumor, therefore, keratinizes like the middle portion of the outer root sheath. Our own case shows the typical above-mentioned clinical and histological signs of the pilar tumor.
毛母质瘤主要发生于老年女性。它是一种孤立性病变,多数情况下位于头皮。尽管病程通常较长,但毛母质瘤极少发生转移。小的肿瘤看起来像“皮脂腺囊肿”,大的及非常大的肿瘤则被诊断为鳞状细胞癌。在这些病例中,如果性别、年龄和部位相符,就可以直接做出正确诊断。显微镜检查显示鳞状上皮相互交织的小叶,其中心出现毛母质或外毛根鞘囊肿的突然角化。因此,毛母质瘤的角化方式类似于外毛根鞘的中部。我们自己的病例显示了上述典型的毛母质瘤临床和组织学特征。