Sica D A, Harford A M, Zawada E T
Clin Nephrol. 1984 Aug;22(2):102-4.
Hypertension refractory to standard dialystic maneuvers developed in a 25-year old female who had been on long-term hemodialysis. Lowering the target dry weight and adding antihypertensives did not ameliorate the hypertension. Hypercalcemia, due to vitamin D administration, was discovered and, following its correction, there was subsequent normalization of the blood pressure. This report discusses some of the mechanisms whereby calcium can interface with blood pressure regulatory mechanisms in individuals with end stage renal disease.
一名长期接受血液透析的25岁女性出现了对标准透析措施无效的高血压。降低目标干体重并添加抗高血压药物并未改善高血压情况。发现因服用维生素D导致高钙血症,在纠正高钙血症后,血压随后恢复正常。本报告讨论了钙在终末期肾病患者中与血压调节机制相互作用的一些机制。