Fraser I
Ann R Coll Surg Engl. 1984 Sep;66(5):321-6.
Strain gauges and electrodes to detect intestinal motility were attached to the terminal ileum, right and left sides of the colon in Rhesus monkeys. Baseline recordings were made. An obstruction device was applied to the left colon at a laparotomy. Compromise of the bowel lumen leading to total obstruction occurred at 13 +/- 2 days. As obstruction progressed, contractions decreased in the terminal ileum and right colon but increased in the left colon proximal to the obstruction. Distention wave forms increased in the colon proximal to the obstruction. Visible intestinal movement, borborygmi and signs suggesting colic were accompanied by a motility phenomenon, simultaneous mass actions, not seen in normal unobstructed bowel. The obstructed segment was resected and an anastomosis made. The motility recordings revealed that postoperative ileus persisted for less than 48 hours and motility returned to normal significantly earlier than after a control laparotomy.
应变片和电极被附着于恒河猴的回肠末端、结肠左右两侧，用于检测肠道蠕动。进行了基线记录。在剖腹手术中，在左结肠应用了阻塞装置。在13±2天出现导致完全阻塞的肠腔受压情况。随着阻塞进展，回肠末端和右结肠的收缩减少，但在阻塞近端的左结肠中增加。阻塞近端结肠的扩张波形增加。可见的肠道运动、肠鸣音和提示绞痛的体征伴随着一种蠕动现象，即同步的大量活动，这在正常未阻塞的肠道中未见。切除阻塞段并进行吻合。蠕动记录显示，术后肠梗阻持续时间不到48小时，且蠕动恢复正常的时间明显早于对照剖腹手术后。
