Roessner A, Kolde G, Stahl K, Blanke G, van Husen N, Themann H
Acta Hepatogastroenterol (Stuttg). 1978 Apr;25(2):119-23.
Normal liver biopsies of 14 volunteers were investigated ultrastructural morphometrically. Besides the determination of morphometric baseline data for comparative purposes particular emphasis was placed on the question, if morphometric evaluations of human livers yield reliable results in spite of the higher range of distribution than in experimental liver material. The results showed that the surface of the smooth endoplasmic reticulum of human liver is significantly greater than the surface of rough endoplasmic reticulum. Otherwise the morphometric data of the human liver tissue did not differ essentially to the values of the laboratory rat. The variance analytical consideration of the mean evaluated from the data of the 14 liver biopsies indicated that the standard error of nearly all proved parameters was less than 10% of the mean. The results suggest that ultrastructural morphometric evaluation of human liver biopsy samples yield reliable results provided the samples investigated are sufficiently extensive.
对14名志愿者的正常肝脏活检组织进行了超微结构形态计量学研究。除了为比较目的确定形态计量学基线数据外，特别强调了一个问题，即尽管人类肝脏的分布范围比实验性肝脏材料更广，但对人类肝脏进行形态计量学评估是否能得出可靠的结果。结果表明，人类肝脏滑面内质网的表面积明显大于粗面内质网的表面积。否则，人类肝脏组织的形态计量学数据与实验大鼠的值没有本质差异。对14份肝脏活检数据评估得出的平均值进行方差分析表明，几乎所有已证实参数的标准误差均小于平均值的10%。结果表明，只要所研究的样本足够广泛，对人类肝脏活检样本进行超微结构形态计量学评估就能得出可靠的结果。
