Kumar A
Indian J Lepr. 1984 Apr-Jun;56(2):313-8.
The widely experienced poor treatment compliance by leprosy out-patients has interfered with effective leprosy control and contributed to the problem of drug (dapsone) resistance. This paper summarises (1) the pattern of treatment compliance by rural and urban patients in a leprosy hyperendemic area, and (2) various methods to monitor the treatment compliance, especially under field conditions. Two simple methods of monitoring the dapsone intake by patients viz. "Physical verification of DDS tablets with patients" and "paper spot test", when applied together, by a field worker in the field, were found to be operationally very feasible, economical and acceptable; and had good correlation with each other. Thus these methods are recommended to be used on large scale in leprosy control programme. The paper spot test was found to be 98% reliable, when compared with DDS/Cr. ratio estimation. In addition, communities and patients be continuously educated about leprosy and its control; and for the optimal utilization of medical care services by patients, they should be organized in background of the consumers.
麻风病门诊患者普遍存在治疗依从性差的问题，这干扰了麻风病的有效控制，并导致了耐药（氨苯砜）问题。本文总结了（1）麻风病高度流行地区农村和城市患者的治疗依从性模式，以及（2）监测治疗依从性的各种方法，特别是在现场条件下。实地工作人员在现场同时应用两种简单的监测患者氨苯砜摄入量的方法，即“与患者一起实际核查氨苯砜片剂”和“试纸斑点试验”，发现这两种方法在操作上非常可行、经济且可接受；并且彼此之间具有良好的相关性。因此，建议在麻风病控制项目中大规模使用这些方法。与氨苯砜/肌酐比值估计相比，试纸斑点试验的可靠性为98%。此外，应持续对社区和患者进行麻风病及其控制方面的教育；为了使患者能够最佳地利用医疗服务，应将他们组织成消费者群体。
