Lesinski S G
Laryngoscope. 1984 Nov;94(11 Pt 1):1443-6.
To study the most appropriate ossicular reconstruction of patients with an absent malleus, a comparison was made utilizing a homograft tympanic membrane with attached malleus and shaped incus (TMMI) columella and the alternative use of underlay fascia tympanoplasty with a cartilage covered TORP. Forty-six patients were reconstructed with a homograft TMMI and 38 with cartilage covered TORP and underlay fascia technique; 4.5 years postoperatively, 84% of those patients reconstructed with a homograft TMMI maintained an average A/B gap of 25 dB or better. Though 1 year postoperatively the TORP hearing results were satisfactory, only 18% of the TORP patients maintained a hearing level within 25 dB A/B gap at 4 years postoperatively. Primary causes of failure of the TORP were instability with migration off the stapes footplate, protrusion or extrusion through the TM and finally, long-term softening and bending secondary to biodegradation of the Plastipore. The discouraging long-term hearing results found in the TORP patients in this study confirm similar findings reported in 1982 by Smyth in a 5 year follow-up on 116 TORP patients.
为研究锤骨缺失患者最合适的听骨链重建方法,对采用带有附着锤骨和塑形砧骨的同种异体鼓膜(TMMI)柱状体以及使用软骨覆盖的全听骨赝复物(TORP)加鼓膜内植筋膜的替代方法进行了比较。46例患者采用同种异体TMMI进行重建,38例采用软骨覆盖的TORP加鼓膜内植筋膜技术进行重建;术后4.5年,采用同种异体TMMI重建的患者中有84%平均气骨导差维持在25dB或更低。虽然术后1年TORP的听力结果令人满意,但术后4年只有18%的TORP患者气骨导差维持在25dB以内。TORP失败的主要原因是镫骨足板移位导致的稳定性问题、通过鼓膜的突出或挤出,以及最终由于Plastipore生物降解导致的长期软化和弯曲。本研究中TORP患者令人沮丧的长期听力结果证实了Smyth在1982年对116例TORP患者进行5年随访时报告的类似发现。