Evans R J, Wilhoit S C, Suratt P M
Comput Programs Biomed. 1984;18(3):227-34. doi: 10.1016/0010-468x(84)90053-9.
A computerized data acquisition and analysis routine was developed to quantitate respiratory disturbances in sleeping patients. Polysomnographic recordings of patients consisted of electroencephalograms, electro-occulograms, submental electromyograms, air flow at the nose and mouth, esophageal pressure, and oxyhemoglobin saturation (SaO2). SaO2, a physiological effect of ventilatory airflow, was sampled every two seconds and stored on disk during the night's study for subsequent analysis. Wild points in the data file can be marked so that they will be skipped during analysis. Patient polysomnographs were scored manually for sleep stage by a sleep technician. A file was then created containing the scored sleep information with time marks corresponding to each change in sleep stage during the study. An analysis routine used this file to develop indices of sleep apnea, severity for combinations or specific stages of sleep. These indices were: (A) number of oxyhemoglobin desaturation episodes per hour; (B) average maximum desaturation per episode; and (C) desaturation index, the product of (A) and (B). A graph was plotted showing cumulative sleep time at given SaO2 values. The degree of sleep apnea can be determined using these indices.
开发了一种计算机化的数据采集和分析程序，用于对睡眠患者的呼吸紊乱进行定量分析。患者的多导睡眠图记录包括脑电图、眼电图、颏下肌电图、口鼻气流、食管压力和氧合血红蛋白饱和度（SaO2）。SaO2是通气气流的一种生理效应，每两秒采样一次，并在夜间研究期间存储在磁盘上以供后续分析。数据文件中的异常点可以被标记，以便在分析过程中跳过。睡眠技术人员会手动对患者的多导睡眠图进行睡眠阶段评分。然后创建一个文件，其中包含评分后的睡眠信息以及与研究期间每个睡眠阶段变化相对应的时间标记。一个分析程序使用该文件来制定睡眠呼吸暂停指数、睡眠组合或特定阶段的严重程度指数。这些指数包括：（A）每小时氧合血红蛋白去饱和发作次数；（B）每次发作的平均最大去饱和度；以及（C）去饱和指数，即（A）和（B）的乘积。绘制了一张图表，显示了给定SaO2值下的累计睡眠时间。使用这些指数可以确定睡眠呼吸暂停的程度。
