用于拟合希尔方程的袖珍计算机程序。

Pocket computer program for fitting the Hill equation.

作者信息

Pinto G F, Oestreicher E G

出版信息

Comput Biol Med. 1984;14(4):507-11. doi: 10.1016/0010-4825(84)90052-0.

Abstract

This paper presents a program written in the BASIC language for the Radio Shack TRS-80 PC-1 or the Sharp PC 1211 pocket computers for fitting the Hill equation to experimental data. The program is based on a procedure involving a combination of an optimization technique and non-linear regression. The program determines precisely all three parameters of the Hill equation and in addition, it performs a simulation of the kinetic experiment using the parameter values previously estimated, calculating the sum of squares of residuals.

摘要

本文介绍了一个用BASIC语言编写的程序，该程序适用于Radio Shack TRS - 80 PC - 1或夏普PC 1211袖珍计算机，用于将希尔方程拟合到实验数据。该程序基于一种将优化技术与非线性回归相结合的方法。该程序能精确确定希尔方程的所有三个参数，此外，它还使用先前估计的参数值对动力学实验进行模拟，计算残差平方和。