Hösli E, Schoenenberger G A, Hösli L
Eur Neurol. 1984;23(5):317-20. doi: 10.1159/000115710.
By means of light-microscopic autoradiography, binding sites for the delta sleep-inducing peptide (3H-DSIP) were observed on the soma and processes of cultured brain stem neurones but not on glial cells. Unlabelled DSIP at high concentrations inhibited binding of 3H-DSIP, indicating specific binding of this peptide. Our data suggest that brain stem neurones might possess receptors for the sleep-inducing peptide.
通过光学显微镜放射自显影术,在培养的脑干神经元的胞体和突起上观察到了δ睡眠诱导肽(3H-DSIP)的结合位点,但在胶质细胞上未观察到。高浓度的未标记DSIP抑制了3H-DSIP的结合,表明该肽具有特异性结合。我们的数据表明脑干神经元可能拥有睡眠诱导肽的受体。