Ryeén A C, Schean A, Agell B O
Acta Orthop Scand. 1978 Feb;49(1):98-101. doi: 10.3109/17453677809005733.
A case of arthritis in multiple joints due to B. fragilis ssp. fragilis is described. The patient was a 55-year-old man badly disabled by rheumatoid arthritis. The patient's immune response to the isolated strain was studied and a significant titre reduction during the course of the disease was observed. The serum antibodies of the patient cross-reacted with heterologous strains of B. fragilis ssp. fragilis. It is suggested that indirect immunofluorescence tests against a certain number of B. fragilis strains could be performed with serum from a patient in whom an infection with B. fragilis is suspected.
本文描述了一例由脆弱拟杆菌脆弱亚种引起的多关节关节炎病例。患者为一名55岁男性,因类风湿性关节炎而严重致残。研究了患者对分离菌株的免疫反应,观察到病程中抗体滴度显著降低。患者的血清抗体与脆弱拟杆菌脆弱亚种的异源菌株发生交叉反应。建议对疑似感染脆弱拟杆菌的患者血清进行针对一定数量脆弱拟杆菌菌株的间接免疫荧光试验。