Mattern J, Keppler B, Volm M
Arzneimittelforschung. 1984;34(10):1289-90.
The antitumour activity of diethoxy-(1-phenyl-1,3-butanedionato)titanium (IV) (DBT) in comparison to cis-dichlorodiammine platinum (cisplatin, cis-DDP) and cyclophosphamide (CTX) against human breast, colo-rectal and lung tumour lines growing as xenografts in nude mice was investigated. The antitumour activities and toxicities of DBT and cis-DDP are comparable whereas CTX was the most effective agent.
研究了二乙氧基 -（1-苯基-1,3-丁二酮）钛（IV）（DBT）与顺式二氯二氨铂（顺铂，cis-DDP）和环磷酰胺（CTX）相比，对在裸鼠体内作为异种移植物生长的人乳腺癌、结肠直肠癌和肺癌细胞系的抗肿瘤活性。DBT和顺铂的抗肿瘤活性和毒性相当，而CTX是最有效的药物。
