Post-meiotic transcription in mouse testes detected with spermatid cDNA clones.

cDNA clones to poly(A)+ mRNA from spermatids have been obtained to study gene transcription in postmeiotic germ cells. Four cDNA clones detect mRNAs that increase in abundance in post-meiotic germ cells. One clone, pPM459, was shown to correspond to an mRNA that is transcribed after meiosis. Pulse-labelling experiments demonstrate transcription of the message in spermatids. These data constitute further evidence for post-meiotic gene transcription in spermatids.