Feman S S, Turinsky J, Lam K W
Am J Ophthalmol. 1978 Mar;85(3):387-91. doi: 10.1016/s0002-9394(14)77736-0.
We measured immunoreactive insulin concentrations in ocular fluids and serum of 19 patients. In rhegmatogenous retinal detachment patients without diabetes mellitus, the serum insulin level was 7 +/- 2 (SE) microunits/ml and the subretinal fluid insulin levels were mostly undetectable. By contrast, in rhegmatogenous retinal detachment patients with diabetes mellitus, serum insulin was 35 +/- 5 microunits/ml and the subretinal fluid always contained low but detectable amojnts of insulin. The data may suggest a small leak of insulin into the subretinal fluid of rhegmatogenous retinal detachment patients with diabetic retinopathy. In vitrectomy patients with diabetes mellitus there was no insulin in the vitreous in eight out of nine cases.
我们检测了19例患者眼内液和血清中的免疫反应性胰岛素浓度。在无糖尿病的孔源性视网膜脱离患者中，血清胰岛素水平为7±2（标准误）微单位/毫升，视网膜下液中的胰岛素水平大多无法检测到。相比之下，在患有糖尿病的孔源性视网膜脱离患者中，血清胰岛素水平为35±5微单位/毫升，视网膜下液中总是含有少量但可检测到的胰岛素。这些数据可能表明，患有糖尿病性视网膜病变的孔源性视网膜脱离患者的胰岛素会少量渗漏到视网膜下液中。在接受玻璃体切除术的糖尿病患者中，9例中有8例玻璃体内没有胰岛素。
