硬化萎缩性苔藓中的HLA抗原和Bf同种异型
HLA antigens and Bf allotypes in lichen sclerosus et atrophicus.
作者信息
Holt P J, Darke C
出版信息
Tissue Antigens. 1983 Jul;22(1):89-91. doi: 10.1111/j.1399-0039.1983.tb01172.x.
Abstract
A study of the HLA-A, B and DR antigens and properdin factor B allotypes of 26 patients with lichen sclerosus et atrophicus and a normal control population showed an increase in the HLA-Aw31 antigen only. However, when the HLA-A and B frequencies were combined with the results of a previous independent study a significant increase in both HLA-Aw31 and HLA-B40 was noted. These findings suggest an association between lichen sclerosus et atrophicus and the HLA system.
摘要
一项针对26例硬化萎缩性苔藓患者及正常对照人群的HLA - A、B和DR抗原以及备解素因子B同种异型的研究显示，仅HLA - Aw31抗原有所增加。然而，当将HLA - A和B的频率与先前一项独立研究的结果相结合时，发现HLA - Aw31和HLA - B40均显著增加。这些发现提示硬化萎缩性苔藓与HLA系统之间存在关联。
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