单卵双胎女性的外阴硬化性苔藓：一例病例报告及文献复习

Doulaveri Georgeta, Armira Kalliopi, Kouris Anargyros, Karypidis Dimitrios, Potouridou Irene

Department of Dermatology and Venereology, Hospital 'Andreas Sygros', Athens, Greece.

Wound Healing Research Unit, Cardiff University, Cardiff, UK.

Case Rep Dermatol. 2013 Nov 7;5(3):321-5. doi: 10.1159/000356775. eCollection 2013.

Lichen sclerosus et atrophicus is a skin disease of multifactorial etiology which appears in patients with genetic or hormonal predisposition and autoimmune disease. Genetic predisposition is suggested by familial reports of the disease which involve twins, siblings, and mother-daughter/son series. This is a report of the occurrence of lichen sclerosus et atrophicus in monozygotic twin women, suggesting that inheritance is of relevance in the etiology of this disease.

硬化萎缩性苔藓是一种病因多因素的皮肤病，出现在有遗传或激素易感性以及自身免疫性疾病的患者中。该疾病的家族报告，包括双胞胎、兄弟姐妹以及母女/子系列，提示存在遗传易感性。本文报告了一对同卵双胞胎女性均发生硬化萎缩性苔藓，表明遗传因素在该疾病的病因中具有相关性。